Janeane has had many memorable and critically acclaimed roles in films such as The Truth About Cats and Dogs, Wet Hot American Summer, Ratatouille, Steal This Movie, Reality Bites, Romy and Michelle's High School Reunion, Mystery Men, The Ten and The Cable Guy
Janeane also co-authored the best seller Feel This Book, with Ben Stiller.
Janeane was a cast member of the Emmy Award-winning Ben Stiller Show and also received an Emmy nomination for her role as Paula, the acerbic talent booker, on The Larry Sanders Show
During the fall of '94, Janeane joined the cast of Saturday Night Live
Some of Janeane's other television work includes two specials for HBO, FOX’s 24, Mad About You, and the final season of NBC's The West Wing
In addition to acting in film and television, Janeane is an outspoken activist, spoken word performer and stand-up comedy entertainer known and respected around the world
She was instrumental in the successful launching of the first liberal radio network, Air America Radio, where she hosted her own talk show, The Majority Report